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Sex differences in the neurotoxic effects of adenosine A1 receptor antagonism during ethanol withdrawal: reversal with an A1 receptor agonist or an NMDA receptor antagonist.

Author
Abstract
:

Neuronal adaptations that occur during chronic ethanol (EtOH) exposure have been observed to sensitize the brain to excitotoxic insult during withdrawal. The adenosine receptor system warrants further examination in this regard, as recent evidence has implicated adenosine receptor involvement in the behavioral effects of both EtOH exposure and withdrawal.

Year of Publication
:
2008
Journal
:
Alcoholism, clinical and experimental research
Volume
:
32
Issue
:
7
Number of Pages
:
1260-70
ISSN Number
:
0145-6008
URL
:
https://doi.org/10.1111/j.1530-0277.2008.00681.x
DOI
:
10.1111/j.1530-0277.2008.00681.x
Short Title
:
Alcohol Clin Exp Res
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