The University of Notre Dame Nuclear Science Laboratory (NSL) is home to 2 electrostatic accelerators that are used for a variety of studies in nuclear physics. A major focus of these studies is to understand the properties and reactions of nuclei in astrophysical environments. This seminar will focus on these measurements with an emphasis on the direct measurements of reaction cross sections using the St. George Recoil Separator, the precision determination of resonance properties via elastic scattering measurements, and the investigation of reactions on radioactive nuclei using the TwinSol separator. Finally, future plans including the expansion of the NSL and the installation of an underground accelerator will also be discussed.