Colocalization of Galectin-3 With CD147 Is Associated With Increased Gelatinolytic Activity in Ulcerating Human Corneas.
| Author | |
|---|---|
| Abstract |
:
Galectin-3 is a carbohydrate-binding protein known to promote expression of matrix metalloproteinases, a hallmark of ulceration, through interaction with the extracellular matrix metalloproteinase inducer CD147. The aim of this study was to investigate the distribution of galectin-3 in corneas of patients with ulcerative keratitis and to determine its relationship to CD147 and the presence of gelatinolytic activity. |
| Year of Publication |
:
2018
|
| Journal |
:
Investigative ophthalmology & visual science
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| Volume |
:
59
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| Issue |
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1
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| Number of Pages |
:
223-230
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| Date Published |
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2018
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| ISSN Number |
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0146-0404
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| URL |
:
http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.17-23196
|
| DOI |
:
10.1167/iovs.17-23196
|
| Short Title |
:
Invest Ophthalmol Vis Sci
|
| Download citation |
