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PEATH: Single Individual Haplotyping by a Probabilistic Evolutionary Algorithm with Toggling.

Author
Abstract
:

Single individual haplotyping (SIH) is critical in genomic association studies and genetic diseases analysis. However, most genomic analysis studies do not perform haplotype-phasing analysis due to its complexity. Several computational methods have been developed to solve the SIH problem, but these approaches have not generated sufficiently reliable haplotypes.

Year of Publication
:
2018
Journal
:
Bioinformatics (Oxford, England)
Date Published
:
2018
ISSN Number
:
1367-4803
URL
:
https://academic.oup.com/bioinformatics/article-lookup/doi/10.1093/bioinformatics/bty012
DOI
:
10.1093/bioinformatics/bty012
Short Title
:
Bioinformatics
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