Skip to main content

Graphical classification of DNA sequences of HLA alleles by deep learning.

Author
Abstract
:

Alleles of human leukocyte antigen (HLA)-A DNAs are classified and expressed graphically by using artificial intelligence "Deep Learning (Stacked autoencoder)". Nucleotide sequence data corresponding to the length of 822 bp, collected from the Immuno Polymorphism Database, were compressed to 2-dimensional representation and were plotted. Profiles of the two-dimensional plots indicate that the alleles can be classified as clusters are formed. The two-dimensional plot of HLA-A DNAs gives a clear outlook for characterizing the various alleles.

Year of Publication
:
2018
Journal
:
Human cell
Date Published
:
2018
ISSN Number
:
0914-7470
DOI
:
10.1007/s13577-017-0194-6
Short Title
:
Hum Cell
Download citation