There are many clinical situations and pathologies typically treated in secondary care that are closely related to eating disorders (EDs). In fact,secondary care is often the first (and sometimes only) contact patients with EDs have with a healthcare professional. In these situations, EDs can go unnoticed by healthcare professionals treating the patient if they do not have proper training. In this article we will discuss diseases and clinical situations typically managed in secondary care that may be associated with or attributed to EDs. We will discuss how to collect evidence regarding their role in the development or perpetuation of ED, and the preventive measurements that can be taken.