Skip to main content

Oxytocin in young children with Prader-Willi syndrome: Results of a randomized, double-blind, placebo-controlled, crossover trial investigating 3 months of oxytocin.

Author
Abstract
:

Prader-Willi syndrome (PWS) is characterized by hypothalamic dysfunction, hyperphagia and a typical behavioural phenotype, with characteristics of autism spectrum disorder (ASD) like stubbornness, temper tantrums and compulsivity. It has been suggested that the oxytocin system in patients with PWS is dysfunctional. In ASD, intranasal oxytocin treatment has favourable effects on behaviour.

Year of Publication
:
2021
Journal
:
Clinical endocrinology
Volume
:
94
Issue
:
5
Number of Pages
:
774-785
ISSN Number
:
0300-0664
URL
:
https://doi.org/10.1111/cen.14387
DOI
:
10.1111/cen.14387
Short Title
:
Clin Endocrinol (Oxf)
Download citation