Skip to main content

Trimethylsilylethynyl ketones as surrogates for ethynyl ketones in the double Michael reaction.

Author
Abstract
:

Trimethylsilylethynyl ketones can be desilylated in the presence of a tethered carbon diacid and induced to undergo a double Michael reaction in situ. The trimethylsilylethynyl ketones can serve as surrogates of ethynyl ketones that are difficult to prepare or isolate.

Year of Publication
:
2002
Journal
:
The Journal of organic chemistry
Volume
:
67
Issue
:
9
Number of Pages
:
3149-51
Date Published
:
2002
ISSN Number
:
0022-3263
URL
:
https://dx.doi.org/10.1021/jo0163086
DOI
:
10.1021/jo0163086
Short Title
:
J Org Chem
Download citation