Trimethylsilylethynyl ketones as surrogates for ethynyl ketones in the double Michael reaction.
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Abstract |
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Trimethylsilylethynyl ketones can be desilylated in the presence of a tethered carbon diacid and induced to undergo a double Michael reaction in situ. The trimethylsilylethynyl ketones can serve as surrogates of ethynyl ketones that are difficult to prepare or isolate. |
Year of Publication |
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2002
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Journal |
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The Journal of organic chemistry
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Volume |
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67
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Issue |
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9
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Number of Pages |
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3149-51
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Date Published |
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2002
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ISSN Number |
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0022-3263
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URL |
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https://dx.doi.org/10.1021/jo0163086
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DOI |
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10.1021/jo0163086
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Short Title |
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J Org Chem
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