Warfarin and bosentan interaction in a patient with pulmonary hypertension secondary to bilateral pulmonary emboli.
| Author | |
|---|---|
| Abstract |
:
Bosentan is an endothelin-receptor antagonist that reportedly induces both cytochrome P450 (CYP) 3A4 and CYP2C9 enzymes, which are also involved in warfarin metabolism. We present a case report describing a probable drug interaction between warfarin and bosentan in a patient with pulmonary hypertension. |
| Year of Publication |
:
2010
|
| Journal |
:
Clinical therapeutics
|
| Volume |
:
32
|
| Issue |
:
1
|
| Number of Pages |
:
53-6
|
| ISSN Number |
:
0149-2918
|
| URL |
:
https://linkinghub.elsevier.com/retrieve/pii/S0149-2918(10)00005-6
|
| DOI |
:
10.1016/j.clinthera.2010.01.004
|
| Short Title |
:
Clin Ther
|
| Download citation |
