Hypothalamic Sensing of Bile Acids, a Gut Feeling.
| Author | |
|---|---|
| Abstract |
:
Bile acids facilitate dietary fat absorption upon release into the small intestine after a meal. A recent study by Liu and colleagues identifies a gut-brain axis wherein bile acids signal an energy-replete state to hypothalamic AgRP neurons via activation of neuronal FGF receptors, which orchestrate whole-body glucose metabolism. |
| Year of Publication |
:
2018
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| Journal |
:
Trends in endocrinology and metabolism: TEM
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| Volume |
:
29
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| Issue |
:
6
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| Number of Pages |
:
363-366
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| ISSN Number |
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1043-2760
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| URL |
:
https://linkinghub.elsevier.com/retrieve/pii/S1043-2760(18)30021-3
|
| DOI |
:
10.1016/j.tem.2018.02.001
|
| Short Title |
:
Trends Endocrinol Metab
|
| Download citation |
