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Preterm growth restriction and bronchopulmonary dysplasia: the vascular hypothesis and related physiology.

Author
Abstract
:

Approximately 5-10% pregnancies are affected by fetal growth restriction. Preterm infants affected by fetal growth restriction have a higher incidence of bronchopulmonary dysplasia. The present study is the first to measure pulmonary artery thickness and stiffness. The findings show that impaired vasculogenesis may be a contributory factor in the higher incidence of bronchopulmonary dysplasia in preterm growth restricted infants. The study addresses the mechanistic link between fetal programming and vascular architecture and mechanics.

Year of Publication
:
2018
Journal
:
The Journal of physiology
Date Published
:
2018
ISSN Number
:
0022-3751
URL
:
https://doi.org/10.1113/JP276040
DOI
:
10.1113/JP276040
Short Title
:
J Physiol
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