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Loss of Response to Anti-Tumor Necrosis Factor Alpha Therapy in Crohn's Disease Is Not Associated with Emergence of Novel Inflammatory Pathways.

Author
Abstract
:

While monoclonal antibodies against tumor necrosis factor-α (TNFα) are effective in treating Crohn's disease (CD), approximately one-third of patients lose response. The mechanisms underlying this loss of response remain elusive.

Year of Publication
:
2018
Journal
:
Digestive diseases and sciences
Date Published
:
2018
ISSN Number
:
0163-2116
DOI
:
10.1007/s10620-018-4932-8
Short Title
:
Dig Dis Sci
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