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Compromised JMJD6 histone demethylase activity impacts on VHL gene repression in preeclampsia.

Author
Abstract
:

The von Hippel Lindau (VHL) protein is a key executor of the cellular hypoxic response that is compromised in preeclampsia, a serious disorder complicating 5-7% of pregnancies. To date, the mechanisms controlling VHL gene expression in the human placenta remain elusive.

Year of Publication
:
2018
Journal
:
The Journal of clinical endocrinology and metabolism
Date Published
:
2018
ISSN Number
:
0021-972X
DOI
:
10.1210/jc.2017-02197
Short Title
:
J Clin Endocrinol Metab
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