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Microparticulate Caspase-1 Regulates Gasdermin-D and Pulmonary Vascular Endothelial Cell Injury.

Author
Abstract
:

Lung endothelial cell apoptosis and injury occurs throughout all stages of acute lung injury (ALI/ARDS) and impacts disease progression. Caspases 1, 4 and 5 are essential for completion of the apoptotic program known as pyroptosis that also involves pro-inflammatory cytokines.

Year of Publication
:
2018
Journal
:
American journal of respiratory cell and molecular biology
Date Published
:
2018
ISSN Number
:
1044-1549
URL
:
http://www.atsjournals.org/doi/abs/10.1165/rcmb.2017-0393OC?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
DOI
:
10.1165/rcmb.2017-0393OC
Short Title
:
Am J Respir Cell Mol Biol
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