Neither non-toxigenic <i>Staphylococcus aureus</i> nor commensal <i>S. epidermidi</i> activates NLRP3 inflammasomes in human conjunctival goblet cells.
| Author | |
|---|---|
| Abstract |
:
The conjunctiva is a wet mucosal surface surrounding the cornea that is continuously exposed to pathogens. Nevertheless, persistent inflammation is not observed. We examined if the NOD-like receptor pyrin domain 3 (NLRP3) inflammasome functions as a sensor that distinguishes commensal and non-pathogenic bacteria from pathogenic bacteria in human conjunctival goblet cells. |
| Year of Publication |
:
0
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| Journal |
:
BMJ open ophthalmology
|
| Volume |
:
2
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| Issue |
:
1
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| Number of Pages |
:
e000101
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| Date Published |
:
2017
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| DOI |
:
10.1136/bmjophth-2017-000101
|
| Short Title |
:
BMJ Open Ophthalmol
|
| Download citation |