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Association of β-Amyloid and Apolipoprotein E ε4 With Memory Decline in Preclinical Alzheimer Disease.

Author
Abstract
:

Older age, high levels of β-amyloid (Aβ), and the presence of the apolipoprotein E (APOE) ε4 allele are risk factors for Alzheimer disease (AD). However, the extent to which increasing age, Aβ, and ε4 are associated with memory decline remains unclear, and the age at which memory decline begins for Aβ-positive ε4 carriers and noncarriers has not been determined.

Year of Publication
:
2018
Journal
:
JAMA neurology
Date Published
:
2018
ISSN Number
:
2168-6149
URL
:
https://archneur.jamanetwork.com/article.aspx?doi=10.1001/jamaneurol.2017.4325
DOI
:
10.1001/jamaneurol.2017.4325
Short Title
:
JAMA Neurol
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