The Jun/miR-22/HuR regulatory axis contributes to tumourigenesis in colorectal cancer.
| Author | |
|---|---|
| Abstract |
:
Colorectal cancer (CRC) is a severe health problem worldwide. Clarifying the mechanisms for the deregulation of oncogenes and tumour suppressors in CRC is vital for its diagnosis, treatment, prognosis and prevention. Hu antigen R (HuR), which is highly upregulated in CRC, functions as a pivotal oncogene to promote CRC progression. However, the underlying cause of its dysregulation is poorly understood. |
| Year of Publication |
:
2018
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| Journal |
:
Molecular cancer
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| Volume |
:
17
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| Issue |
:
1
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| Number of Pages |
:
11
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| Date Published |
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2018
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| URL |
:
https://molecular-cancer.biomedcentral.com/articles/10.1186/s12943-017-0751-3
|
| DOI |
:
10.1186/s12943-017-0751-3
|
| Short Title |
:
Mol Cancer
|
| Download citation |