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DK St Clair

First name:
DK
Last name:
St Clair
Barone, E. ., Cenini, G. ., Sultana, R. ., Di Domenico, F. ., Fiorini, A. ., Perluigi, M. ., … Butterfield, D. . (2012). Lack of p53 decreases basal oxidative stress levels in the brain through upregulation of thioredoxin-1, biliverdin reductase-A, manganese superoxide dismutase, and nuclear factor kappa-B. Antioxidants & Redox Signaling, 16(12), 1407-20. https://doi.org/10.1089/ars.2011.4124 (Original work published 2012)
Jungsuwadee, P. ., Zhao, T. ., Stolarczyk, E. ., Paumi, C. ., Butterfield, D. ., St Clair, D. ., & Vore, M. . (2012). The G671V variant of MRP1/ABCC1 links doxorubicin-induced acute cardiac toxicity to disposition of the glutathione conjugate of 4-hydroxy-2-trans-nonenal. Pharmacogenetics and Genomics, 22(4), 273-84. https://doi.org/10.1097/FPC.0b013e328350e270
Zhao, Y. ., Miriyala, S. ., Miao, L. ., Mitov, M. ., Schnell, D. ., Dhar, S. ., … St Clair, D. . (2014). Redox proteomic identification of HNE-bound mitochondrial proteins in cardiac tissues reveals a systemic effect on energy metabolism after doxorubicin treatment. Free Radical Biology & Medicine, 72, 55-65. https://doi.org/10.1016/j.freeradbiomed.2014.03.001
Keeney, J. ., Miriyala, S. ., Noel, T. ., Moscow, J. ., St Clair, D. ., & Butterfield, D. . (2015). Superoxide induces protein oxidation in plasma and TNF-α elevation in macrophage culture: Insights into mechanisms of neurotoxicity following doxorubicin chemotherapy. Cancer Letters, 367(2), 157-61. https://doi.org/10.1016/j.canlet.2015.07.023 (Original work published 2015)
Barone, E. ., Cenini, G. ., Di Domenico, F. ., Noel, T. ., Wang, C. ., Perluigi, M. ., … Butterfield, D. . (2015). Basal brain oxidative and nitrative stress levels are finely regulated by the interplay between superoxide dismutase 2 and p53. Journal of Neuroscience Research, 93(11), 1728-39. https://doi.org/10.1002/jnr.23627
Ren, X. ., Keeney, J. ., Miriyala, S. ., Noel, T. ., Powell, D. ., Chaiswing, L. ., … Butterfield, D. . (2019). The triangle of death of neurons: Oxidative damage, mitochondrial dysfunction, and loss of choline-containing biomolecules in brains of mice treated with doxorubicin. Advanced insights into mechanisms of chemotherapy induced cognitive impairment.. Free Radical Biology & Medicine, 134, 1-8. https://doi.org/10.1016/j.freeradbiomed.2018.12.029
Ren, X. ., Boriero, D. ., Chaiswing, L. ., Bondada, S. ., St Clair, D. ., & Butterfield, D. . (2019). Plausible biochemical mechanisms of chemotherapy-induced cognitive impairment ("chemobrain"), a condition that significantly impairs the quality of life of many cancer survivors. Biochimica Et Biophysica Acta. Molecular Basis of Disease, 1865(6), 1088-1097. https://doi.org/10.1016/j.bbadis.2019.02.007 (Original work published 2019)
Yarana, C. ., Thompson, H. ., Chaiswing, L. ., Butterfield, D. ., Weiss, H. ., Bondada, S. ., … St Clair, D. . (2019). Extracellular vesicle-mediated macrophage activation: An insight into the mechanism of thioredoxin-mediated immune activation. Redox Biology, 26, 101237. https://doi.org/10.1016/j.redox.2019.101237
Duncan, M. ., Smith, J. ., Franklin, K. ., Beckett, T. ., Murphy, M. ., St Clair, D. ., … O’Hara, B. . (2012). Effects of aging and genotype on circadian rhythms, sleep, and clock gene expression in APPxPS1 knock-in mice, a model for Alzheimer’s disease. Experimental Neurology, 236(2), 249-58. https://doi.org/10.1016/j.expneurol.2012.05.011
Keller, J. ., Kindy, M. ., Holtsberg, F. ., St Clair, D. ., Yen, H. ., Germeyer, A. ., … Mattson, M. . (1998). Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, 18(2), 687-97. Retrieved from http://www.jneurosci.org/cgi/pmidlookup?view=long&pmid=9425011 (Original work published 1998)