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Jason Collett

Education:
University of Kentucky, Lexington, Kentucky B.S. Biology, 2006
Biography:

My research involves investigating the mechanisms of genetic hypertension.  In particular, I am interested in the interactions between the nuclear and mitochondrial genomes and it's potential role in the development of high blood pressure and cardiovascular disease.

Graduate Training
University of Kentucky, Lexington, Kentucky Ph.D. Biology, 2006-current
Awesome Science Blog
Selected Publications:

Collett JA, Hart AK, Patterson E, Kretzer J, and Osborn JL. Renal angiotensin II type 1 receptor expression and associated hypertension in rats with minimal SHR nuclear genome. Physiological Reports 1: n/a-n/a, 2013.

PubMed Publications*: 
  • JA Collett; Ortiz -Soriano V; X Li; AH Flannery; RD Toto; OW Moe; DP Basile; JA Neyra"Serum IL-17 levels are higher in critically ill patients with AKI and associated with worse outcomes."Critical care (London, England)26.1(2022):107.Details. Full text
  • J Santollo; JA Collett; AA Edwards"The anti-dipsogenic and anti-natriorexigenic effects of estradiol, but not the anti-pressor effect, are lost in aged female rats."Physiological reports9.14(2021):e14948.Details. Full text
  • P Mehrotra; MM Ullah; JA Collett; SL Myers; MR Dwinell; AM Geurts; DP Basile"Mutation of RORγT reveals a role for Th17 cells in both injury and recovery from renal ischemia-reperfusion injury."American journal of physiology. Renal physiology319.5(2020):F796-F808.Details. Full text
  • P Mehrotra; JA Collett; SJ Gunst; DP Basile"Th17 cells contribute to pulmonary fibrosis and inflammation during chronic kidney disease progression after acute ischemia."American journal of physiology. Regulatory, integrative and comparative physiology314.2(2018):R265-R273.Details. Full text
  • AL Kolb; PR Corridon; S Zhang; W Xu; FA Witzmann; JA Collett; GJ Rhodes; S Winfree; D Bready; ZJ Pfeffenberger; JM Pomerantz; T Hato; GT Nagami; BA Molitoris; DP Basile; SJ Atkinson; RL Bacallao"Exogenous Gene Transmission of Isocitrate Dehydrogenase 2 Mimics Ischemic Preconditioning Protection."Journal of the American Society of Nephrology : JASN29.4(2018):1154-1164.Details. Full text
  • P Mehrotra; JA Collett; SD McKinney; J Stevens; CM Ivancic; DP Basile"IL-17 mediates neutrophil infiltration and renal fibrosis following recovery from ischemia reperfusion: compensatory role of natural killer cells in athymic rats."American journal of physiology. Renal physiology312.3(2017):F385-F397.Details. Full text
  • JA Collett; PR Corridon; P Mehrotra; AL Kolb; GJ Rhodes; CA Miller; BA Molitoris; JG Pennington; RM Sandoval; SJ Atkinson; SB Campos-Bilderback; DP Basile; RL Bacallao"Hydrodynamic Isotonic Fluid Delivery Ameliorates Moderate-to-Severe Ischemia-Reperfusion Injury in Rat Kidneys."Journal of the American Society of Nephrology : JASN28.7(2017):2081-2092.Details. Full text
  • JA Collett; P Mehrotra; A Crone; WC Shelley; MC Yoder; DP Basile"Endothelial colony-forming cells ameliorate endothelial dysfunction via secreted factors following ischemia-reperfusion injury."American journal of physiology. Renal physiology312.5(2017):F897-F907.Details. Full text
  • JA Collett; DO Traktuev; P Mehrotra; A Crone; S Merfeld-Clauss; KL March; DP Basile"Human adipose stromal cell therapy improves survival and reduces renal inflammation and capillary rarefaction in acute kidney injury."Journal of cellular and molecular medicine21.7(2017):1420-1430.Details. Full text
  • DP Basile; JA Collett; MC Yoder"Endothelial colony forming cells and proangiogenic cells: clarifying definitions and their potential role in mitigating acute kidney injury."Acta physiologica (Oxford, England)(2017):Details. Full text
  • P Mehrotra; JB Patel; CM Ivancic; JA Collett; DP Basile"Th-17 cell activation in response to high salt following acute kidney injury is associated with progressive fibrosis and attenuated by AT-1R antagonism."Kidney international88.4(2015):776-84.Details. Full text
  • BM Franklin; L Xiang; JA Collett; MK Rhoads; JL Osborn"Open problem-based instruction impacts understanding of physiological concepts differently in undergraduate students."Advances in physiology education39.4(2015):327-34.Details. Full text
  • JA Collett; AK Hart; E Patterson; J Kretzer; JL Osborn"Renal angiotensin II type 1 receptor expression and associated hypertension in rats with minimal SHR nuclear genome."Physiological reports1.5(2013):e00104.Details. Full text
  • JA Collett; JK Paulose; VM Cassone; JL Osborn"Kidney-Specific Reduction of Oxidative Phosphorylation Genes Derived from Spontaneously Hypertensive Rat."PloS one10.8(0):e0136441.Details. Full text
  • DP Basile; JA Collett"Orai1: A New Therapeutic Target for the Acute Kidney Injury-to-Chronic Kidney Disease Transition."Nephron146.3(0):264-267.Details. Full text
* Publications are automatically pulled from pubmed.gov based on a user-specific query. Results may include incorrect citations. See: Tutorial on improving PubMed results.